![]() prostate-specific membrane antigen positron emission tomography and axumin scan) can supplant a bone scan if performed first High-risk: technetium bone scan, CT abdomen/pelvis if MSKCC nomogram predicts >10% probability of lymph node involvement.Unfavorable intermediate-risk: technetium bone scan, CT abdomen/pelvis if MSKCC nomogram predicts >10% probability of lymph node involvement. ![]() Favorable intermediate-risk: CT abdomen/pelvis if Memorial Sloan Kettering Cancer Center (MSKCC) nomogram predicts >10% probability of lymph node involvement.Staging workup as recommended by the National Comprehensive Cancer Network (NCCN) on the basis of risk grouping: No evidence of disease beyond the prostate and/or seminal vesicles (i.e., no suspicious pelvic lymph nodes or presence of metastatic disease outside the pelvis).Histologically confirmed, clinical localized adenocarcinoma of the prostate.GROUP II: Patients undergo 5 fractions of MRI-guided SBRT over 14 days in the absence of disease progression or unacceptable toxicity.Īfter completion of study treatment, patients are followed up every 3 months for 1 year, every 6 months for 4 years, and then yearly thereafter. GROUP I: Patients undergo 5 fractions of CT-guided SBRT over 14 days in the absence of disease progression or unacceptable toxicity. OUTLINE: Patients are randomized to 1 of 2 groups. To observe the proportion of SBRT fractions for which on-line adaptive radiotherapy is required due to changes in organ-at-risk anatomy. To determine whether there are differences in 5-year biochemical recurrence-free survival (BCRFS) following MRI-guided SBRT. To quantify the temporal changes in patient-reported quality of life (QOL) outcomes, as assessed by the Expanded Prostate Cancer Index-26 (EPIC-26), International Prostate Symptom Scores (IPSS), and Sexual Health Inventory for Men (SHIM) QOL indices, following MRI-guided SBRT. To determine whether there are differences in 5-year cumulative incidences of late grade >= 2 GU and GI physician-reported toxicity, following MRI-guided SBRT versus CT-guided SBRT. To determine whether there are differences in acute grade >= 2 gastrointestinal (GI) toxicity as assessed by the Common Terminology Criteria for Adverse Events (CTCAE) version 4.03 scale, following MRI-guided SBRT versus CT-guided SBRT. To determine whether (MRI)-guided stereotactic body radiotherapy (SBRT) improves acute physician-scored genitourinary (GU) toxicity when compared with standard computed tomography (CT)-guided SBRT for prostate cancer (PCa). Why Should I Register and Submit Results?.Getting started with PhotoMirage is incredibly easy and addictively fun. In this tutorial, you’ll learn how to transform an image into a captivating animation in just a few quick steps, with PhotoMirage’s intuitive tools.Ĭlick on any of the images below to view full-size. When you first open up PhotoMirage you’ll be greeted by a handy Welcome Guide, packed with helpful video tutorials and other learning content, as well as a gallery of user photo animations to inspire you. The first thing you want to do once you have PhotoMirage open is bring an image in. Drag and drop your photo right into your working area, to get started in no time.Go to the File menu and choose New or Open.Click the Open button in the middle of your workspace to browse for an image on your system.You can work with any JPEG, GIF, PNG, BMP, TIFF or RAW image. The first set of tools you’ll use are the Animation tools, found under the Animation icon, which is clicked by default when you first start. Now, click, drag and release to draw Motion Arrows over the parts of the image you want to animate. Make sure you draw the arrows in the direction you want to see movement. Next, click the Anchor Point icon, and click to plot Anchor Points around the parts of the image you want to keep still.Ĭlick the Play button in the Control bar along the bottom when you are ready to preview your animation. Of course, you may want to refine your animation if your first attempt isn’t perfect, and that’s where a number of other handy tools will come into play. Under the Animation icon, you can edit and delete Motion Arrows and Anchor Points you’ve previously plotted, as well as adjust the speed of your animation. With Motion arrow icon selected, click on an already plotted Motion Arrow on your image, and move it. Click the Delete icon to delete a Motion arrow or Anchor Point by clicking on it.Īnd then drag the Speed slider back and forth to adjust the speed of your animation. The Mask tool is an alternative way to isolate the regions of your photo that you want to keep still.Ĭlick the Mask tool. Increase your brush size using the brush slider and then click and hold to mask the area to remain motionless. ![]()
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